ODCs

Cytoscape Web

Click node...

Familial melanoma

8 OMIM references -
6 associated genes
12 signs/symptoms

PROTEIN INTERACTIONS: 1

Beckwith-Wiedemann syndrome due to CDKN1C mutation

1 associated gene
No signs/symptoms info

Familial melanoma

Beckwith-Wiedemann syndrome due to CDKN1C mutation

CDK4	(UniProt - OMIM)		CDKN1C	(UniProt - OMIM)
CDKN2A	(UniProt - OMIM)
CDKN2B	(UniProt - OMIM)
CDKN2D	(UniProt - OMIM)
MC1R	(UniProt - OMIM)
TERT	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	CDK4	(0.65)	CDKN1C

Citations in the biomedical literature:

Familial melanoma		Beckwith-Wiedemann syndrome due to CDKN1C mutation

	Classification (Orphanet): - Rare eye disease - Rare genetic disease - Rare oncologic disease - Rare skin disease		Classification (Orphanet): - Rare cardiac disease - Rare developmental defect during embryogenesis - Rare genetic disease - Rare maxillo-facial surgical disease - Rare oncologic disease - Rare otorhinolaryngologic disease - Rare renal disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: unknown Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: - Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal dominant

	External references: 8 OMIM references - No MeSH references		External references: No OMIM references No MeSH references

Familial melanoma
	Very frequent - Capillary hemangioma / nevus / naevus flammeus / port-wine stain - Melanoma Frequent - Anomalies of the lymphatic system - Dry / squaly skin / exfoliation - Excessive freckling - Hair and scalp anomalies Occasional - Autosomal dominant inheritance - Breast neoplasm / tumor / carcinoma / cancer - Estomach / gastric neoplasm / tumor / carcinoma / cancer - Extrapyramidal syndrome - Pancreatic / pancreas neoplasm / tumor / carcinoma / cancer - Retinopathy
Beckwith-Wiedemann syndrome due to CDKN1C mutation
(no data available)